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erickyegon/README.md

Erick Kiprotich Yegon

Epidemiologist & Data Scientist · Real-World Evidence · Causal Inference · Healthcare AI & Analytics

LinkedIn ORCID Portfolio Email

📍 Richmond, Kentucky, USA  |  🇺🇸 U.S. Permanent Resident — No Sponsorship Required


What I Do

I have spent 17+ years in epidemiology, global health analytics, data science and agentic AI, underpinned by doctoral training in epidemiology. I build the analysis and the system around it: cohort and survival studies on real-world data, causal designs for policy questions, and the pipelines, models and apps that put results in front of decision makers.

Core areas (each links to a repo that shows it):


Real-World Evidence & Oncology

Project What it shows Stack
oncology-rwe-nsclc · report NSCLC survival pipeline on synthetic EHR data (Synthea → OMOP CDM → dbt → R), benchmarked against 172,582 U.S. patients from SEER. Documents a case where the synthetic data failed validation: unmodified Synthea staged every lung cancer as stage I. R · OMOP CDM · dbt · PostgreSQL
nsclc-rwd-truth-recovery Companion project: a custom generator with a known truth, rule-based line-of-therapy derivation (98.1% whole-sequence exact match against truth), IPTW, an immortal-time-bias demonstration, and a 10-seed Monte-Carlo bias and coverage study. Python · lifelines · scikit-learn
incretin-access-value · site Public-data study of Medicaid coverage of Wegovy and Zepbound: 12.2 additional prescriptions per 1,000 enrollees per quarter (95% CI 8.4 to 16.0) and a net budget impact of about $161.3 million over five years for a 1-million-enrollee program. Tested warehouse, Quarto report, interactive budget model. PostgreSQL · dbt · R · Quarto · Shiny

Healthcare Data Science & ML

Project Description Stack
Immunization Defaulter Risk Engine Live App XGBoost pipeline predicting vaccine defaulter risk for 6,864 children across 4,672 CHW areas in Kenya. Per-patient SHAP explainability, isotonic calibration (ECE 0.023), PSI drift monitoring, FastAPI serving, Streamlit dashboard. Python · XGBoost · SHAP · FastAPI · PostgreSQL · MLflow · Optuna
Databricks Medicare Lakehouse Medicare Advantage lakehouse: medallion ETL, CMS HCC v28 risk adjustment, XGBoost + SHAP, Unity Catalog governance. Databricks · Delta Lake · Python
Community Health Intelligence Platform Community health lakehouse for Kenya's CHW program: medallion pipeline, Unity Catalog row-level security, AI/BI Genie, dashboard. Databricks · Delta Lake · dbt · Airflow
Insurance Premium Prediction End-to-end ML pipeline with CI/CD, MLflow tracking and SHAP explainability. Python · XGBoost · MLflow · SageMaker
Within Reach #TidyTuesday analysis of hospital access across 11,422 U.S. cities, with a live Shiny app. R · Shiny

AI & LLM Systems

Project Description Stack
Clinical Document Intelligence FDA drug-label RAG with 5-stage retrieval, multi-agent orchestration, clinical guardrails and 54 automated tests. Python · FastAPI · ChromaDB
AgentCare Six-agent LangGraph orchestration for patient administration and care coordination. Python · LangGraph · FastAPI · Next.js
Women's Health RAG RAG over Demographic and Health Survey reports. Python · LangChain · LangGraph · pgvector
AI-Powered Research Assistant RAG platform for scientific papers with modular LangGraph workflows. Python · LangGraph · Pinecone
Healthcare Q&A RAG Platform Healthcare knowledge retrieval with vector search and role-based access. Python · FastAPI · ChromaDB
Multimodal PDF RAG System Document intelligence with OCR, table extraction and semantic search. Python · FastAPI · React

Microsoft Fabric & Power BI

Project Description Stack
CertiAce Retail Analytics Fabric portfolio project covering the DP-600 domains: medallion (Bronze/Silver/Gold) architecture over 555K rows, semantic model with DAX measures, KQL real-time monitoring, RLS/OLS and deployment pipelines. Microsoft Fabric · OneLake · KQL · DAX · Power BI
E-Commerce Intelligence Platform Lakehouse pipeline: 1.7M rows, 6 relational tables, medallion architecture, conversion and segmentation models tracked in MLflow. Databricks · Delta Lake · MLflow

Impact at a Glance

What I built Result
Immunization defaulter risk engine (Kenya MOH eCHIS) ROC-AUC 0.892 · 6,864 children · 4,672 CHW areas · live app
Medicaid obesity-drug coverage study +12.2 prescriptions per 1,000 enrollees per quarter (95% CI 8.4 to 16.0); about $161.3M net over five years per 1M enrollees · incretin-access-value
Oncology RWD pipeline validated against a known truth 98.1% line-of-therapy exact match; 10-seed Monte-Carlo bias and coverage · nsclc-rwd-truth-recovery
CertiAce Retail Analytics (Fabric portfolio) Medallion lakehouse · 555K rows · DAX · KQL · RLS/OLS · deployment pipelines
ML predictive models for health outcomes 30% improvement in prediction accuracy
Automated data pipelines (AWS + PostgreSQL + dbt) Reporting turnaround: 10–14 days → near real-time; manual processing down 40%
Causal inference and RWE studies 25+ studies (PSM, IPW, DiD, ITS, TMLE) informing $2M+ in annual resource allocation
Data and analytics for community health programs Programs reaching 8.5M+ people in Kenya, Uganda and Burkina Faso
Peer-reviewed publications 30+, including The Lancet (2025)

Skills and where to see them

Skill Evidence
Survival analysis (Kaplan–Meier, Cox, time-varying exposure) oncology-rwe-nsclc · nsclc-rwd-truth-recovery
Pharmacoepidemiology methods (IPTW, immortal-time bias, E-value) nsclc-rwd-truth-recovery
Causal inference (difference-in-differences, event study) incretin-access-value
OMOP CDM, dbt, PostgreSQL oncology-rwe-nsclc · incretin-access-value
Budget impact / health economics incretin-access-value
R, Quarto, Shiny incretin-access-value · within-reach
Python, scikit-learn, lifelines nsclc-rwd-truth-recovery
XGBoost, SHAP, calibration, drift monitoring immunization-defaulter-risk-engine
MLflow, Optuna immunization-defaulter-risk-engine · insurance-premium-prediction-ml
FastAPI, Docker, Streamlit immunization-defaulter-risk-engine
AWS SageMaker insurance-premium-prediction-ml
PyTorch (CNN) FreshHarvest
RAG, vector search (ChromaDB, pgvector, Pinecone) clinical-doc-intelligence · womens-health-rag · AI-Powered-Research-Assistant
LangChain, LangGraph, multi-agent systems AgentCare · clinical-doc-intelligence
Microsoft Fabric, OneLake, KQL, deployment pipelines certace-fabric-analytics
Power BI, DAX, RLS/OLS certace-fabric-analytics
Databricks, Delta Lake, Unity Catalog community-health-intelligence-platform · databricks-medicare-lakehouse
Airflow community-health-intelligence-platform

Education

Degree Institution
PhD, Epidemiology Jomo Kenyatta University of Agriculture and Technology (JKUAT)
MSc, Health Systems Management Kenya Methodist University
BSc, Statistics University of Nairobi

Certifications

Certification Issuer Status
Microsoft Certified: Power BI Data Analyst Associate (PL-300) Microsoft ✅
Google Data Analytics Professional Certificate Google ✅
CITI Program: Human Subjects Research; Good Clinical Practice; Big Data and Data Science Research Ethics CITI Program ✅
Microsoft Fabric Analytics Engineer (DP-600) Microsoft In preparation

How I Work

I pair statistical rigor with working software. I check my methods against a known answer where I can, document where a data source fails validation, and ship analyses as reproducible pipelines. The NSCLC truth-recovery study and the Synthea-versus-SEER benchmark are examples.


Open To

Hands-on and leadership roles across real-world evidence, epidemiology, health data science and applied AI:

  • Real-World Evidence Scientist / Epidemiologist
  • Senior / Principal / Lead Data Scientist (healthcare and clinical)
  • Population Health Analytics Lead
  • Analytics Engineer / Microsoft Fabric Engineer
  • Director / VP, Data & Analytics

Target sectors: Pharma · Biotech · CRO · Health Systems · Payers & Insurers · Health Tech · Global Health · Federal Contractors


📩 keyegon@gmail.com  |  🔗 LinkedIn  |  🆔 ORCID

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